姓名:蒋皓
学历:博士
职称:副研究员
专业方向:生物医用材料
Email: hustjh@hust.edu.cn
教育与工作经历
2018. 06-现在 华中科技大学,化学与化工学院,副研究员
2015. 11-2018. 02 德国,杜伊斯堡-埃森大学化学系,博士后,合作导师:Carsten Schmuck教授
2013. 10-2015. 10 以色列,本-古里安大学化学系,博士后,合作导师:Raz Jelinek教授
2012. 09-2013. 09 中国科学技术大学高分子科学与工程系,博士后,合作导师:邹纲教授
2007. 09-2012. 07 中国科学技术大学,高分子科学与工程系,博士,导师:邹纲教授和张其锦教授
2003. 09-2007. 07 中国科学技术大学,高分子科学与工程系,本科
研究领域与兴趣
1. 多功能多肽纳米药物用于抗肿瘤治疗
2. 具有高效广谱抗菌功能的抗菌肽水凝胶用于慢性伤口愈合
已发表论文
1. Guo, C.#; Zhang, Y.#; Li, Y.; Zhang, L.; Jiang, H.*; Tao, J.; Zhu, J., Gold nanoparticle-guarded large-pore mesoporous silica nanocomposites for delivery and controlled release of cytochrome c. Journal of colloid and interface science 2021, 589, 34-44.
2. Zhang, Y.; Guo, C.; Liu, L.; Xu, J.; Jiang, H.; Li, D.; Lan, J.; Li, J.; Yang, J.; Tu, Q.; Sun, X.; Alamgir, M.; Chen, X.; Shen, G.; Zhu, J.; Tao, J.*, ZnO-based multifunctional nanocomposites to inhibit progression and metastasis of melanoma by eliciting antitumor immunity via immunogenic cell death. Theranostics 2020, 10, 11197-11214.
3. Yin, X.; Chen, Z.; Chen, Y.; Xie, Y.; Xiong, B.; Jiang, H.*; Zhu, J.*, Lipidated gemini peptide amphiphiles with enhanced loading capacity and cell membrane affinity for drug delivery. Colloids and surfaces. B, Biointerfaces 2020, 195, 111271.
4. Xiong, B.; Chen, Z.; Yin, X.; Wang, Y.; Jiang, H.*; Zhu, J.*, Diffusion behavior of peptide amphiphiles containing different numbers of alkyl tails at a hydrophobic solid-liquid interface: single molecule tracking investigation. Soft matter 2020, 16, 4444-4450.
5. Du, S.#; Zhou, N.#; Gao, Y.; Xie, G.; Du, H.; Jiang, H.; Zhang, L.*; Tao, J.*; Zhu, J.*, Bioinspired hybrid patches with self-adhesive hydrogel and piezoelectric nanogenerator for promoting skin wound healing. Nano Research 2020, 13, 2525-2533.
6. Chen, Y.; Ma, T.; Liu, P.; Ren, J.; Li, Y.; Jiang, H.*; Zhang, L.; Zhu, J.*, NIR-Light-Activated Ratiometric Fluorescent Hybrid Micelles for High Spatiotemporally Controlled Biological Imaging and Chemotherapy. Small 2020, 16, 2005667.
7. Jiang, H.; Hu, X.-Y.; Mosel, S.; Knauer, S. K.; Hirschhäuser, C.; Schmuck, C.*, A Branched Tripeptide with an Anion-Binding Motif as a New Delivery Carrier for Efficient Gene Transfection. ChemBioChem 2019, 20, 1410-1416.
8. Hussain, M.#; Xie, J.#; Wang, K.; Wang, H.; Tan, Z.; Liu, Q.; Geng, Z.; Shezad, K.; Noureen, L.; Jiang, H.; Xu, J.*; Zhang, L.; Zhu, J.*, Biodegradable Polymer Microparticles with Tunable Shapes and Surface Textures for Enhancement of Dendritic Cell Maturation. Acs Applied Materials & Interfaces 2019, 11, 42734-42743.
9. Chen, Y.; Ren, J.; Tian, D.; Li, Y.*; Jiang, H.; Zhu, J.*, Polymer-Upconverting Nanoparticle Hybrid Micelles for Enhanced Synergistic Chemo-Photodynamic Therapy: Effects of Emission- Absorption Spectral Match. Biomacromolecules 2019, 20, 4044-4052.
10. Jiang, H.; Ehlers, M.; Hu, X.-y.; Zellermann, E.; Schmuck, C.*, Dimensional control of supramolecular assemblies of diacetylene-derived peptide gemini amphiphile: from spherical micelles to foamlike networks. Soft Matter 2018, 14, 5565-5571.
11. Jiang, H.; Hu, X.-Y.; Schlesiger, S.; Li, M.; Zellermann, E.; Knauer, S. K.; Schmuck, C.*, Morphology-Dependent Cell Imaging by Using a Self-Assembled Diacetylene Peptide Amphiphile. Angewandte Chemie-International Edition 2017, 56, 14526-14530.
12. Jiang, H.; Jelinek, R.*, Hierarchical Assembly of Polydiacetylene Microtube Biosensors Mediated by Divalent Metal Ions. Chempluschem 2016, 81, 119-124.
13. Jiang, H.#; Hershtig, G.#; Richter, S.*; Jelinek, R.*, Light-Induced Conductivity in a Solution-Processed Film of Polydiacetylene and Perylene Diimide. Journal of Physical Chemistry Letters 2016, 7, 1628-1631.
14. Jiang, H.; Jelinek, R.*, Mixed Diacetylene/Octadecyl Melamine Nanowires Formed at the Air/Water Interface Exhibit Unique Structural and Colorimetric Properties. Langmuir 2015, 31, 5843-5850.
15. Jiang, H.*; Hu, W.; Li, J.; Yang, G.; Zou, G.*; Zhang, Q., Tunable morphology and surface wettability of an amphiphilic azobenzene derivative and its melamine-induced self-assembly. Supramolecular Chemistry 2015, 27, 181-190.
16. Yang, G.; Han, L.; Jiang, H.; Zou, G.*; Zhang, Q.; Zhang, D.*; Wang, P.; Ming, H., Enantioselective synthesis of helical polydiacetylenes in the visible light region. Chemical Communications 2014, 50, 2338-2340.
17. Xu, Y.; Jiang, H.; Zhang, Q.; Wang, F.; Zou, G.*, Helical polydiacetylene prepared in the liquid crystal phase using circular polarized ultraviolet light. Chemical Communications 2014, 50, 365-367.
18. Xia, H.; Xu, Y.; Yang, G.; Jiang, H.; Zou, G.*; Zhang, Q., A Reversible Multi-Stimuli-Responsive Fluorescence Probe and the Design for Combinational Logic Gate Operations. Macromolecular Rapid Communications 2014, 35, 303-308.
19. Kootery, K. P.; Jiang, H.; Kolusheva, S.; Vinod, T. P.; Ritenberg, M.; Zeiri, L.; Volinsky, R.; Malferrari, D.; Galletti, P.; Tagliavini, E.; Jelinek, R.*, Poly(methyl methacrylate)-Supported Polydiacetylene Films: Unique Chromatic Transitions and Molecular Sensing. Acs Applied Materials & Interfaces 2014, 6, 8613-8620.
20. Jiang, H.; Vinod, T. P.; Jelinek, R.*, Spontaneous Assembly of Extremely Long, Horizontally-Aligned, Conductive Gold Micro-Wires in a Langmuir Monolayer Template. Advanced Materials Interfaces 2014, 1, 1400187.
21. Jiang, H.; Jelinek, R.*, Dramatic Shape Modulation of Surfactant/Diacetylene Microstructures at the Air-Water Interface. Chemistry-a European Journal 2014, 20, 16747-16752.
22. Hu, W.#; Chen, Y.#; Jiang, H.; Li, J.; Zou, G.*; Zhang, Q.; Zhang, D.*; Wang, P.; Ming, H., Optical Waveguide Based on a Polarized Polydiacetylene Microtube. Advanced Materials 2014, 26, 3136-3141.
23. Wang, J.; Yang, G.; Jiang, H.; Zou, G.*; Zhang, Q., Photo-responsive cholesterol-substituted diacetylenic organogels: morphology tuning, photo-switching and photo-polymerization. Soft Matter 2013, 9, 9785-9791.
24. Li, J.; Jiang, H.; Yu, Z.; Xia, H.; Zou, G.*; Zhang, Q.; Yu, Y., Multifunctional Uniform Core-Shell Fe3O4@mSiO2 Mesoporous Nanoparticles for Bimodal Imaging and Photothermal Therapy. Chemistry-an Asian Journal 2013, 8, 385-391.
25. Li, J.; Jiang, H.; Hu, W.; Xia, H.; Zou, G.*; Zhang, Q., Photo-controlled Hierarchical Assembly and Fusion of Coumarin-containing Polydiacetylene Vesicles. Macromolecular Rapid Communications 2013, 34, 274-279.
26. Rao, J.; Jiang, H.; Wang, J.; Zou, G.*; Zhang, Q., Tunable nonlinear optical properties of PDA/Ag composite vesicles based on reversible host-guest interaction. Chemical Physics Letters 2012, 539, 70-73.
27. Li, J.; Yu, Z.; Jiang, H.; Zou, G.*; Zhang, Q., Photo and pH dual-responsive polydiacetylene smart nanocontainer. Materials Chemistry and Physics 2012, 136, 219-224.
28. Li, J.; Jiang, H.; Hu, W.; Zou, G.*; Zhang, Q., Morphology modulation in an azobenzene based supramolecular amphiphiles system. Journal of Photochemistry and Photobiology a-Chemistry 2012, 245, 28-32.
29. Jiang, H.; Chen, X.; Pan, X.; Zou, G.*; Zhang, Q., Regulation of Supramolecular Chirality in Co-Assembled Polydiacetylene LB Films with Removable Azobenzene Derivatives. Macromolecular Rapid Communications 2012, 33, 773-778.
30. Hu, W.; Jiang, H.; Li, J.; Zou, G.*; Zhang, Q., Novel Chromatic Transitions of Azobenzene-Functionalized Polydiacetylene Aggregates in 1,2-Dichlorobenzene Solution. Macromolecular Chemistry and Physics 2012, 213, 2582-2589.
31. Pan, X.; Wang, Y.; Jiang, H.; Zou, G.*; Zhang, Q., Benzo-15-crown-5 functionalized polydiacetylene-based colorimetric self-assembled vesicular receptors for lead ion recognition. Journal of Materials Chemistry 2011, 21, 3604-3610.
32. Pan, X.; Jiang, H.; Wang, Y.; Lei, Z.; Zou, G.*; Zhang, Q.; Wang, K., Supramolecular chirality formation of bisazobenzene-substituted polydiacetylene LB films. Journal of Colloid and Interface Science 2011, 354, 880-886.
33. Jiang, H.; Pan, X.-J.; Lei, Z.-Y.; Zou, G.*; Zhang, Q.-J.; Wang, K.-Y., Control of supramolecular chirality for polydiacetylene LB films with the command azobenzene derivative monolayer. Journal of Materials Chemistry 2011, 21, 4518-4522.
34. Zou, G.*; Jiang, H.; Zhang, Q.; Kohn, H.; Manaka, T.; Iwamoto, M., Chiroptical switch based on azobenzene-substituted polydiacetylene LB films under thermal and photic stimuli. Journal of Materials Chemistry 2010, 20, 285-291.
35. Pan, X.; Jiang, H.; Wang, Y.; Zou, G.*; Zhang, Q., Chiral Polydiacetylene Assembles. Progress in Chemistry 2010, 22, 2014-2023.
36. Jiang, H.; Wang, Y.; Ye, Q.; Zou, G.*; Su, W.; Zhang, Q., Polydiacetylene-based colorimetric sensor microarray for volatile organic compounds. Sensors and Actuators B-Chemical 2010, 143, 789-794.
37. Jiang, H.; Pan, X.-J.; Lei, Z.-Y.; Zou, G.*; Zhang, Q.-J.; Wang, K.-Y., Photocontrol of chiroptical properties of polydiacetylene carrying azobenzene in the side chain. Chemical Physics Letters 2010, 500, 100-103.
38. Chen, X.; Jiang, H.; Wang, Y.; Zou, G.*; Zhang, Q., beta-Cyclodextrin-induced fluorescence enhancement of a thermal-responsive azobenzene modified polydiacetylene vesicles for a temperature sensor. Materials Chemistry and Physics 2010, 124, 36-40.
39. Zou, G.*; Jiang, H.; Kohn, H.; Manaka, T.; Iwamoto, M., Control and modulation of chirality for azobenzene-substituted polydiacetylene LB films with circularly polarized light. Chemical Communications 2009, 5627-5629.